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Dose-ranging studies identified 2.5-15 mg weekly as the therapeutic range, with 5-day half-life confirming once-weekly dosing feasibility

2014 Oct

Mechanisms of Action: How MOTS-C Remodels Metabolism Understanding the MOTS-c dosage chart requires understanding the mechanisms it targets, because dose-response relationships in peptide biology are rarely linear

Sanchez C, Bay-Jensen A-C, Pap T, Dvir-Ginzberg M, Quasnichka H, Barrett-Jolley R, et al

In animal studies, Dihexa was found to be approximately 1,000 times more potent than BDNF (brain-derived neurotrophic factor) at promoting synapse formation

The reality is more nuanced: The critical difference is clinical validation depth